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Honors Theses from 2024

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Phenanthrene Jamboree, Alexander D. Roth

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SPRTN Metalloprotease as a Target to Sensitize Cancer Cells to Crosslinking Chemotherapy, Cole J. Turner

Honors Theses from 2022

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Analyzing the Free Energy of Ions Sampling a Voltage Gated Sodium Ion Channel, Isabel Varghese

Honors Theses from 2021

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Use of Small Molecule Fanconi Anemia Pathway Inhibitors as Sensitizing Agents to Laromustine., Sam W. Marchant

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The Quantitative Assessment of Pond Scum: An examination of the biogeochemistry of phosphorus cycling in the Belgrade lakes, Abbey M. Sykes

Honors Theses from 2020

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Single-Nucleotide Polymorphisms Associated with Bitter Taste Perception and Influence on Food and Drink Preferences, Maria K. Armillei

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Identifying Metabolites as Markers of Fatigue in Athletes, Christopher D. George

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Spectroscopic Characterization of Atmospheric Aerosol Particle Mimics, Hayley Elizabeth Gibson

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Environmental Impacts of Oil Spills: Weathering, Emissions, and Atmospheric Processing of Crude Oil, Hannah Q. Karp

Honors Theses from 2019

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Synthesis of Oxacalix[2]arene[2]naphthalimides and Exploration of Anion-Pi Interactions for Colorimetric Fluoride Sensing, Joseph A. Forzano

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Generation and Reactions of Cyclopropyl Vinylidene Carbenes, Nguyen Nhat Thu Le

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Detecting Cyanobacteria Toxins: The Human Health Impact of an Environmental Problem, Lillian E. Naimie

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Characterization of DNA-Protein Crosslinks formed by Epichlorohydrin, Tenzin Passang

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Development of a Chemical Genetic Screen to Identify Compounds that Enhance Laromustine Cytotoxicity, Xiaoou Wang

Honors Theses from 2018

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Examining molecular markers of fertility in the male germline of the soapberry bug, Jadera haematoloma, Danielle M. Smith

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Haloferax volcanii for carotenoid production, Erika Smith

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Silicon and tin substituted halocyclopropanes: approaches to new carbenes and strained cyclic allenes, Noura Srour

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Investigating phosphorylation patterns and their effect on the activity of transcription factor TaABF1 in imbibing cereal grains, Grace Uwase

Honors Theses from 2017

Modeling the Quantum Dynamics of Hydrogen Transfer Reactions in Enzyme Catalysis, Emma G. Berger

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Photochemical Generation of Carbenes and Ketenes from Phenanthrene-based Precursors Part I: Dimethylalkylidene Part II: Diphenylketene, Tarini S. Hardikar and Tarini Hardikar

Honors Theses from 2016

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Phenanthrene...With a Twist!, Nicholas S. Kim

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Part I: Photochemical Generation of Cyclohexyne from a Hydrocarbon Precursor Part II: A Triptycenyl Flower, Daniel Maurer

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Development of a Chemical Genetic Screen to Determine Synergistic Compounds with Laromustine in Treating Glioblastoma Multiforme Cultured Cells, Ryan Weeks

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Experimental and Computational Study of Methylphenylvinylidene and Its Rearrangements, Xi Yang

Honors Theses from 2015

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Experimental and Computational Investigation of Selected β-Hydroxy Carbenes, Joseph D. DeAngelo

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An Investigation of BAG3 Knockdown and its Effects on the Cytotoxicity of Laromustine, Colin Sheehan

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Generation of 2-Adamantylidenecarbene from a Phenanthrene-Based Precursor, Christine E. Wamsley

Honors Theses from 2014

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Structural Characterization of the Major Guanosine-Guanosine Cross-Link Formed by Epichlorohydrin, Edward Chuang

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Optimization of a Chemical Genetic Screen to Identify Druggable Targets in U138 Cells Treated with Laromustine, Kathryn Coe

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Influence of the Sea Surface Microlayer on Ozone Deposition Velocity, Kathryn Moore

Honors Theses from 2013

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Investigating the effects of BAG3 knockdown on the cytotoxicity of the anticancer drug Laromustine, Kayla Gross

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Investigating the Interaction of Zinc-Finger Peptides and Nicked DNA Using Phage Display, Rachel Maria Guerra

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Life on the Edge: Biotic and Abiotic Production of Hydrogen Production Along the Chemical Gradient, Carly Elise Hallowell

Honors Theses from 2010

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Cytotoxicity of Diepoxybutane and Epichlorohydrin in Relation to Stages of the Cell Cycle, Bethany L. Bartley

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Analysis of the Electron Withdrawing Capability of Acetylene Groups for Promoting Nucleophilic Aromatic Substitution, Eric D. Braunstein

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A Method for the Photochemical Production of Superoxide Radicals in Aqueous Acetone-Ethanol Solutions, and the Simultaneous Chemiluminescent Detection of Superoxide and Hydrogen Peroxide, Brian DiMento

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Patterns of Apoptotic Poly(ADP-ribose) Polymerase Cleavage Induced by Laromustine and its Analogs, Adam N. Paine

Honors Theses from 2009

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Changes in Apoptotic Gene Expression Induced by DNA Cross-Linkers, Jordanne B. Dunn

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The Effects of Exogenous Insulin and Exercise on Glucose and Lactate Metabolism in the Brown Anole, Anolis sagrei, Kristen Marie Hitchcox

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Mechanisms of Cytotoxicity of Diepoxybutane, Epichlorohydrin and 1-(Chloroethenyl)oxirane, Rebecca D. Kamins

Honors Theses from 2008

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Effects of the anticancer agent Cloretazine on human apurinic endonuclease-1 activity, Jennifer L. Bushee

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Investigating the Effects of Mifepristone (RU486) in the Behavioral, Hormonal and Central Responses to Acute Stress, Aynara Chávez Muñoz

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The Selective Synthesis of Oxacalix[6]arenes and the Exploration of Azacalix[n]arenes, W. Christian Crannell

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Photochemical Generation and Intramolecular Chemistry of β-Alkoxycarbenes, Kimberly Graves

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Reactions of Atomic Carbon with Acid Chlorides, Daniel B. Herrick

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Temperature and magnetic field dependence of the electronic excitations in the nickel chain compound NINO, Lucas LaViolet

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Diepoxybutane and epibromohydrin bend DNA towards the major groove, Erin McGowan

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Pressure Perturbation Calorimetry and Guest-Host Chemistry of NDMG and N-MAP with p-Sulfonatocalix[6]arene, Cassandra Newell

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Using azahetercyclic electrophiles to synthesize novel Bicyclooxacalixarenes and Oxacalix[2]N-hexylnaphthalimide[2]naphthyridines, Doug Rooke

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Inhibition of cellular thioredoxin reductase by the anticancer prodrug cloretazine, Tyler R. Schleicher

Honors Theses from 2007

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Towards the Synthesis of Biomimetic Tungsten Complexes, Eric Paul Bergh

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Biogeochemical model for the eutrophication of East Pond, Maine, Bernadette Bibber

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Concomitant polymorphism in 1,2-bis(9-anthryl)acetylene, Rebecca Goldstein

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Salmoninae Commensal Bacteria Show a Positive Correlation Between Antibiotic Resistance and Mercury Resistance Profiles, E. McClure

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Quantitative PCR reveals preferential nuclear DNA alkylation by epichlorohydrin in the chicken genome, Adam Newman

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Intramolecular Chemistry of ß-acetoxyethylidene and Photochemical Generation of Vinylidenes, Jennifer M. Nguyen

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Detailed Mechanistic and Optimization of the Photochemical Production Method of Superoxide, Ta-Chung Ong

Honors Theses from 2006

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Investigating the mechanisms of a novel ribosomal RNA degradation system, Daniel Fowler

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A Computational Study of the Reactivity Differences of Two Carbonyl Dianions, Sylvia Haller

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Characterization of the Wheat Grain PKABA1-Interacting Protein TaWD40, Natalie Wayne

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Synthesis of 2-oxo-16-(3', 4'-methylenedioxyphenyl)-trans-15-hexadecene, Adelajda Zorba

Honors Theses from 2005

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The Synthesis of Biomimetic Tungsten and Molybdenum Complexes, John Sterling Cole III

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Guest-host chemistry of p-sulfonatocalix[6]arene and nizatidine, Galia Debelouchina

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Synthesis and characterization of di- and tri-oxacalix[4]arenes, Michael Feldman

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Towards the production of a mutant stylar ribonuclease that inhibits the self-incompatibility response, Yan Kung

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Analytical tools for studying phosphorus and nitrogen lake nutrient dynamics and their application to the field, Ivan Mihajlov

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Synthetic approaches to rigid "rod-and-panel" macrocycles, Timothy Newhouse

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Investigation of Iron (III) desferrioxamine B oxalate ligand exchange by UV-vis spectroscopy: the next step in developing a quantitative analytical method for measuring bioavailable iron in marine ecosystems, Ken L. Pitter

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Photochemical generation of 2-methoxy-2methylpropylidene and its rearrangement pathways, Stanislav Presolski

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The Synthesis and Characterization of Bicyclooxacalixarenes, Kevin J. Selby

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An Analysis of the Effect of Carbon Dioxide on the Decay Rates of Superoxide, Michael Jay Walsh

Honors Theses from 2004

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Mapping of Diepoxybutane Damage in the Cytochrome b Domain of Mitochondrial DNA and the β-globin Domain of Nuclear Chicken DNA Using Quantitative PCR, Justin Juskewitch

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Reaction of epichlorohydrin and epibromohydrin with synthetic DNA oligomers, Keith Romano

Honors Theses from 2003

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Double stranded DNA-binding studies of potential Rhodium(ll) antitumor complexes, Amity Elizabeth Burr

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Quantitative Analysis of Diepoxybutane Damage within the Chicken β-globin Domain, André M. Pilon

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Application of the Chan-Evans diaryl ether synthesis to the formation of Bis(bibenzyls), Eric Rosenthal

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Flanking Sequences Modulate Diepoxide Cross-linking Efficiencies at the 5'-GNC sSte, Gregory A. Sawyer

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Synthesis of Montiporynes A and B, Traci Jenelle Speed

Honors Theses from 2002

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Synthesis and DNA binding of CIS and TRANS-RuCl2 (DMSO)4, Thomas Curran

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Investigations of Intramolecular Copper (I)-arene Interactions using a NS2-macrocyclic Ligand with Different Pendant Aryl Arms, Paul J. Lee

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Photochemical generation and chemistry of α-Acetoxycarbene, Jonathan Mann

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Purification of the HMG1 protein and investigation of its interactions with diepoxide cross-linked DNA, Gayle Pageau

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Effect of 6-Thioguanine and Methyl-6-Thioguanine on stability of DNA duplexes, Mabaera Rodwell

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The Photochemical Generation and Intramolecular Chemistry of β-Acetoxycarbene, Martin John Schnermann

Honors Theses from 2001

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Exploratory chemistry in route to aromatic natural products, Nicholas P. Bizier

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Quantification of nanomolar superoxide in aqueous solution : flow injection analysis using the chemiluminescent reagent MCLA., Nathan Boland

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Metal ion stabilization of G-tetrads containing 6-thioguanosine, Julia Drees

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Photochemical generation and intramolecular chemistry of 2-hydroxy-2-methylpropylidene, Robin Farlow

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Photochemical degradation of 2,4-D and atrazine in well-defined media, Asher D. Ghertner

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Isolation and characterization of chromium- and cobalt-binding peptides, Michael J. Jose

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Study of the effects of CO2(g) on the Fe(II)-luminol chemiluminescence system: application to ultra-trace analysis of Fe(II), Sara Beth Lovitz

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Role of organic peroxides in ocean waters and measuring hydrogen peroxide in ocean waters using chemiluminescent flow-injection analysis method, Christopher Morgan

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Probing the capabilities of copper complexes with nitrogen and sulfur containing macrocyclic ligands as aziridination catalysts, Jonathan Natkin

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Structural analysis of 6-thioguanine in duplex DNA by NMR spectroscopy, Heather Olson

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Synthetic approach to hexaoxa[6]peristylanes. A novel DDQ-induced oxidative rearrangement, Douglas Arthur Otte

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Flanking Sequence Effects on DNA Interstrand Cross-linking Preferences of Diepoxides, Subhashini Srivatsan

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Structural Analysis of a DNA Duplex Containing 6-Thiodeoxyguanosine by N NMR Spectroscopy and EPR Spectroscopy, Baskut O. Tuncak

Honors Theses from 2000

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Determination of the wavelength dependence on the metal catalyzed degradation of the herbicide atrazine, Timothy Bertram

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DNA interstrand cross-linking by a diepoxide mycotoxin, Jacob Conklin

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Interactions of Ti(IV) and Sn(IV) Organometallic Complexes with Double-stranded DNA, Katherine MacDonald Davies