Date of Award

1968

Document Type

Senior Scholars Paper (Colby Access Only)

Department

Colby College. Chemistry Dept.

Advisor(s)

George D. Maier

Abstract

The investigation of renal hypertension has led to the enzyme renin. At present renin can only be properly assayed by bioassay with a live animal which as been fitted in some manner with a device for measuring blood pressure. One common method is the rat assay. This assay requires careful anaesthesia, skilled surgical preparation of the animal, and several hours in which to complete the procedure, Even so, the assay in the hands of the most practiced technician has a precision of only 5 to 15%. It was the purpose of this senior scholar project to study several possible chemical methods of assay.

Keywords

Renin, chemistry, biology

Comments

Full-text download restricted to Colby College campus only.

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