Event Title
The Effects of Acute Ethanol Exposure on the Innate Immune System of Zebrafish
Location
Diamond 141
Start Date
30-4-2015 1:20 PM
End Date
30-4-2015 2:25 PM
Project Type
Presentation- Restricted to Campus Access
Description
Previous research has shown that ethanol consumption results in a decrease in innate immune activity in mice. In this study, I examine the effects of acute ethanol exposure on the innate immune activity in zebrafish, an effective model organism for immunological study. Zebrafish were exposed to a 1% ethanol solution for one hour and then sacrificed. Their innate immune cells were harvested and exposed to fluorescently labelled pHrodo E. coli to track the phagocytic activity of the innate cells via FACS. It appears that acute ethanol exposure is actually promoting phagocytic activity in zebrafish.
Faculty Sponsor
Judy Stone
Sponsoring Department
Colby College. Biology Dept.
CLAS Field of Study
Natural Sciences
Event Website
http://www.colby.edu/clas
ID
1135
The Effects of Acute Ethanol Exposure on the Innate Immune System of Zebrafish
Diamond 141
Previous research has shown that ethanol consumption results in a decrease in innate immune activity in mice. In this study, I examine the effects of acute ethanol exposure on the innate immune activity in zebrafish, an effective model organism for immunological study. Zebrafish were exposed to a 1% ethanol solution for one hour and then sacrificed. Their innate immune cells were harvested and exposed to fluorescently labelled pHrodo E. coli to track the phagocytic activity of the innate cells via FACS. It appears that acute ethanol exposure is actually promoting phagocytic activity in zebrafish.
https://digitalcommons.colby.edu/clas/2015/program/420