Author (Your Name)

Peter Densen, Colby Colle

Date of Award


Document Type

Senior Scholars Paper (Open Access)


Colby College. Chemistry Dept.


Reid, Evan B


The following paper contains a history of tetronic acids and includes a discussion on the methods of their synthesis, theoretical considerations concerning their unusual acidity, their oxidation, and the problem of their oxidative intermediate. The possible synthetic routes leading to the oxidative intermediate, a-alkyl- a-hydroxy tetronic acid is proposed. Chemical and spectroscopic evidence is presented for the existence of a-alkyl- a -hydroxy tetronic acid obtained by one of the proposed synthetic methods. Actual proof for the existence of this compound awaits a quantitative chemical analysis. A further experiment is suggested which would answer the question of whether or not during the oxidation of tetronic acids the ring opens and splits out carbon dioxide before or after the formation of the diketones.


Lactones, Oxidation