Date of Award
Honors Thesis (Open Access)
Colby College. Chemistry Dept.
Jeffrey L. Katz
It is well known that electron withdrawing groups, such as nitro or carbonyl groups, activate benzene rings for nucleophilic aromatic substitution. However, little research has been done to investigate the electron withdrawing capability of acetylene groups for substitution of aromatic halides. Experimental and computational investigations on the reactivity of halogenated phenylacetylenes with oxygen and other nucleophiles will be described.
Acetylene, Ethynyl, Electron Withdrawing Group, Nucleophilic Aromatic Substitution
Recommended CitationBraunstein, Eric D., "Analysis of the Electron Withdrawing Capability of Acetylene Groups for Promoting Nucleophilic Aromatic Substitution" (2010). Honors Theses. Paper 580.
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