Date of Award
Senior Scholars Paper (Colby Access Only)
Colby College. Chemistry Dept.
George D. Maier
The investigation of renal hypertension has led to the enzyme renin. At present renin can only be properly assayed by bioassay with a live animal which as been fitted in some manner with a device for measuring blood pressure. One common method is the rat assay. This assay requires careful anaesthesia, skilled surgical preparation of the animal, and several hours in which to complete the procedure, Even so, the assay in the hands of the most practiced technician has a precision of only 5 to 15%. It was the purpose of this senior scholar project to study several possible chemical methods of assay.
Renin, chemistry, biology
Recommended CitationMcDonald, Bruce B., "A Chemical Assay for Renin" (1968). Senior Scholar Papers. Paper 455.
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