Date of Award

2010

Document Type

Honors Thesis (Open Access)

Department

Colby College. Chemistry Dept.

Advisor(s)

Jeffrey L. Katz

Abstract

It is well known that electron withdrawing groups, such as nitro or carbonyl groups, activate benzene rings for nucleophilic aromatic substitution. However, little research has been done to investigate the electron withdrawing capability of acetylene groups for substitution of aromatic halides. Experimental and computational investigations on the reactivity of halogenated phenylacetylenes with oxygen and other nucleophiles will be described.

Keywords

Acetylene, Ethynyl, Electron Withdrawing Group, Nucleophilic Aromatic Substitution

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