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Honors Theses from 2016

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Phenanthrene...With a Twist!, Nicholas S. Kim

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Part I: Photochemical Generation of Cyclohexyne from a Hydrocarbon Precursor Part II: A Triptycenyl Flower, Daniel Maurer

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Development of a Chemical Genetic Screen to Determine Synergistic Compounds with Laromustine in Treating Glioblastoma Multiforme Cultured Cells, Ryan Weeks

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Experimental and Computational Study of Methylphenylvinylidene and Its Rearrangements, Xi Yang

Honors Theses from 2015

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Experimental and Computational Investigation of Selected β-Hydroxy Carbenes, Joseph D. DeAngelo

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An Investigation of BAG3 Knockdown and its Effects on the Cytotoxicity of Laromustine, Colin Sheehan

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Generation of 2-Adamantylidenecarbene from a Phenanthrene-Based Precursor, Christine E. Wamsley

Honors Theses from 2014

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Structural Characterization of the Major Guanosine-Guanosine Cross-Link Formed by Epichlorohydrin, Edward Chuang

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Optimization of a Chemical Genetic Screen to Identify Druggable Targets in U138 Cells Treated with Laromustine, Kathryn Coe

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Influence of the Sea Surface Microlayer on Ozone Deposition Velocity, Kathryn Moore

Honors Theses from 2013

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Investigating the effects of BAG3 knockdown on the cytotoxicity of the anticancer drug Laromustine, Kayla Gross

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Investigating the Interaction of Zinc-Finger Peptides and Nicked DNA Using Phage Display, Rachel Maria Guerra

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Life on the Edge: Biotic and Abiotic Production of Hydrogen Production Along the Chemical Gradient, Carly Elise Hallowell

Honors Theses from 2010

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Cytotoxicity of Diepoxybutane and Epichlorohydrin in Relation to Stages of the Cell Cycle, Bethany L. Bartley

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Analysis of the Electron Withdrawing Capability of Acetylene Groups for Promoting Nucleophilic Aromatic Substitution, Eric D. Braunstein

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A Method for the Photochemical Production of Superoxide Radicals in Aqueous Acetone-Ethanol Solutions, and the Simultaneous Chemiluminescent Detection of Superoxide and Hydrogen Peroxide, Brian DiMento

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Patterns of Apoptotic Poly(ADP-ribose) Polymerase Cleavage Induced by Laromustine and its Analogs, Adam N. Paine

Honors Theses from 2009

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Changes in Apoptotic Gene Expression Induced by DNA Cross-Linkers, Jordanne B. Dunn

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The Effects of Exogenous Insulin and Exercise on Glucose and Lactate Metabolism in the Brown Anole, Anolis sagrei, Kristen Marie Hitchcox

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Mechanisms of Cytotoxicity of Diepoxybutane, Epichlorohydrin and 1-(Chloroethenyl)oxirane, Rebecca D. Kamins

Honors Theses from 2008

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Effects of the anticancer agent Cloretazine on human apurinic endonuclease-1 activity, Jennifer L. Bushee

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Investigating the Effects of Mifepristone (RU486) in the Behavioral, Hormonal and Central Responses to Acute Stress, Aynara Chávez Muñoz

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The Selective Synthesis of Oxacalix[6]arenes and the Exploration of Azacalix[n]arenes, W. Christian Crannell

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Photochemical Generation and Intramolecular Chemistry of β-Alkoxycarbenes, Kimberly Graves

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Reactions of Atomic Carbon with Acid Chlorides, Daniel B. Herrick

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Temperature and magnetic field dependence of the electronic excitations in the nickel chain compound NINO, Lucas LaViolet

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Diepoxybutane and epibromohydrin bend DNA towards the major groove, Erin McGowan

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Pressure Perturbation Calorimetry and Guest-Host Chemistry of NDMG and N-MAP with p-Sulfonatocalix[6]arene, Cassandra Newell

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Using azahetercyclic electrophiles to synthesize novel Bicyclooxacalixarenes and Oxacalix[2]N-hexylnaphthalimide[2]naphthyridines, Doug Rooke

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Inhibition of cellular thioredoxin reductase by the anticancer prodrug cloretazine, Tyler R. Schleicher

Honors Theses from 2007

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Towards the Synthesis of Biomimetic Tungsten Complexes, Eric Paul Bergh

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Biogeochemical model for the eutrophication of East Pond, Maine, Bernadette Bibber

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Concomitant polymorphism in 1,2-bis(9-anthryl)acetylene, Rebecca Goldstein

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Salmoninae Commensal Bacteria Show a Positive Correlation Between Antibiotic Resistance and Mercury Resistance Profiles, E. McClure

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Quantitative PCR reveals preferential nuclear DNA alkylation by epichlorohydrin in the chicken genome, Adam Newman

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Intramolecular Chemistry of ß-acetoxyethylidene and Photochemical Generation of Vinylidenes, Jennifer M. Nguyen

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Detailed Mechanistic and Optimization of the Photochemical Production Method of Superoxide, Ta-Chung Ong

Honors Theses from 2006

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Investigating the mechanisms of a novel ribosomal RNA degradation system, Daniel Fowler

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A Computational Study of the Reactivity Differences of Two Carbonyl Dianions, Sylvia Haller

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Characterization of the Wheat Grain PKABA1-Interacting Protein TaWD40, Natalie Wayne

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Synthesis of 2-oxo-16-(3', 4'-methylenedioxyphenyl)-trans-15-hexadecene, Adelajda Zorba

Honors Theses from 2005

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The Synthesis of Biomimetic Tungsten and Molybdenum Complexes, John Sterling Cole III

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Guest-host chemistry of p-sulfonatocalix[6]arene and nizatidine, Galia Debelouchina

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Synthesis and characterization of di- and tri-oxacalix[4]arenes, Michael Feldman

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Towards the production of a mutant stylar ribonuclease that inhibits the self-incompatibility response, Yan Kung

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Analytical tools for studying phosphorus and nitrogen lake nutrient dynamics and their application to the field, Ivan Mihajlov

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Synthetic approaches to rigid "rod-and-panel" macrocycles, Timothy Newhouse

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Investigation of Iron (III) desferrioxamine B oxalate ligand exchange by UV-vis spectroscopy: the next step in developing a quantitative analytical method for measuring bioavailable iron in marine ecosystems, Ken L. Pitter

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Photochemical generation of 2-methoxy-2methylpropylidene and its rearrangement pathways, Stanislav Presolski

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The Synthesis and Characterization of Bicyclooxacalixarenes, Kevin J. Selby

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An Analysis of the Effect of Carbon Dioxide on the Decay Rates of Superoxide, Michael Jay Walsh

Honors Theses from 2004

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Mapping of Diepoxybutane Damage in the Cytochrome b Domain of Mitochondrial DNA and the β-globin Domain of Nuclear Chicken DNA Using Quantitative PCR, Justin Juskewitch

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Reaction of epichlorohydrin and epibromohydrin with synthetic DNA oligomers, Keith Romano

Honors Theses from 2003

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Double stranded DNA-binding studies of potential Rhodium(ll) antitumor complexes, Amity Elizabeth Burr

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Quantitative Analysis of Diepoxybutane Damage within the Chicken β-globin Domain, André M. Pilon

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Application of the Chan-Evans diaryl ether synthesis to the formation of Bis(bibenzyls), Eric Rosenthal

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Flanking Sequences Modulate Diepoxide Cross-linking Efficiencies at the 5'-GNC sSte, Gregory A. Sawyer

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Synthesis of Montiporynes A and B, Traci Jenelle Speed

Honors Theses from 2002

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Synthesis and DNA binding of CIS and TRANS-RuCl2 (DMSO)4, Thomas Curran

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Investigations of Intramolecular Copper (I)-arene Interactions using a NS2-macrocyclic Ligand with Different Pendant Aryl Arms, Paul J. Lee

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Photochemical generation and chemistry of α-Acetoxycarbene, Jonathan Mann

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Purification of the HMG1 protein and investigation of its interactions with diepoxide cross-linked DNA, Gayle Pageau

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Effect of 6-Thioguanine and Methyl-6-Thioguanine on stability of DNA duplexes, Mabaera Rodwell

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The Photochemical Generation and Intramolecular Chemistry of β-Acetoxycarbene, Martin John Schnermann

Honors Theses from 2001

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Exploratory chemistry in route to aromatic natural products, Nicholas P. Bizier

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Quantification of nanomolar superoxide in aqueous solution : flow injection analysis using the chemiluminescent reagent MCLA., Nathan Boland

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Metal ion stabilization of G-tetrads containing 6-thioguanosine, Julia Drees

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Photochemical generation and intramolecular chemistry of 2-hydroxy-2-methylpropylidene, Robin Farlow

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Photochemical degradation of 2,4-D and atrazine in well-defined media, Asher D. Ghertner

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Isolation and characterization of chromium- and cobalt-binding peptides, Michael J. Jose

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Study of the effects of CO2(g) on the Fe(II)-luminol chemiluminescence system: application to ultra-trace analysis of Fe(II), Sara Beth Lovitz

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Role of organic peroxides in ocean waters and measuring hydrogen peroxide in ocean waters using chemiluminescent flow-injection analysis method, Christopher Morgan

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Probing the capabilities of copper complexes with nitrogen and sulfur containing macrocyclic ligands as aziridination catalysts, Jonathan Natkin

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Structural analysis of 6-thioguanine in duplex DNA by NMR spectroscopy, Heather Olson

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Synthetic approach to hexaoxa[6]peristylanes. A novel DDQ-induced oxidative rearrangement, Douglas Arthur Otte

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Flanking Sequence Effects on DNA Interstrand Cross-linking Preferences of Diepoxides, Subhashini Srivatsan

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Structural Analysis of a DNA Duplex Containing 6-Thiodeoxyguanosine by N NMR Spectroscopy and EPR Spectroscopy, Baskut O. Tuncak

Honors Theses from 2000

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Determination of the wavelength dependence on the metal catalyzed degradation of the herbicide atrazine, Timothy Bertram

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DNA interstrand cross-linking by a diepoxide mycotoxin, Jacob Conklin

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Interactions of Ti(IV) and Sn(IV) Organometallic Complexes with Double-stranded DNA, Katherine MacDonald Davies

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H2O2/iron/UV catalyzed degradation of the herbicide 2,4-Dichlorophenoxyacetic acid, Chaz Langelier

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Determination of nizatidine-guest complexation constants and computer aided molecular design, Carolyn J. Mordas

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A Computational Approach to Determining Stability Constants for Transition Metal Ion Complexes, Jason St. Clair

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A Catechol Approach to Natural Product Synthesis, Michelle E. Weber

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Cisplatin Interstrand Cross-linking of Defined Sequence Nucleosomal DNA, Erin Elizabeth Wilkes

Honors Theses from 1998

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Approaches to the synthesis of two substituted aromatic natural products, Shana Bondi

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Molecular Design and Association Constants of Nizatidine-Guest Complexes, Elizabeth Corbeil

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Approaches and Methodologies for the Synthesis of Aromatic Natural Products, Christina A. Goudreau

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Alternatives to nitroprusside, William T. Hiscock

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DNA Bending Induced by Diepoxybutane, Elisabeth Aimee Pimentel

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New approches to oxepane systems, Kenneth P. Raiche

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Methods of pentacene and related organic molecules for semiconductor applications, Emily Reith

Honors Theses from 1997

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Signal transduction pathways in Volvox Carteri, Heide Girardin

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Predicting Gibb's free energy changes for chemical processes: interaction of cations with poly-y-glutamate, Stephanie Mann

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Calcium metabolismn in Volvox Carteri, Bridget Anne Neville

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Characterization and purification of a novel calcium binding protein in the nematocysts of Metridium senile, Joshua Oeltjen

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Computational studies of hydroboration: remote functional groups and ring size effects, Sarah Liberty Olbrich

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Suspended particulate matter and sediment of Penobscot Estuary, Craig M. Pochini

Honors Theses from 1996

Synthesis of a PEG-bipolar-dimyristoylphosphatidylethanoline, Hacho Bohos Bohossian

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Methods and methodologies for organic synthesis, Frank Favaloro